7000smz-2 Vibrotome
 

7000smz-2 Vibrotome

Model 7000smz-2


  • Includes a z-axis calibration unit
  • Z-axis blade adjust minimizer
  • Blade holder angle to user requirement
  • Set start and stop position from blade travel.
  • Vibration speeds from 50 to 120 Hz
  • Amplitudes from 0.5mm to 2.5mm
  • Controlled blade advance at 10microns per sec
  • Manual or automatic operation
  • "Auto" programming by storage of the first slicing
  • Ice water bath easily removed for cleaning
  • Optional LED light and scope for clear observation
 

Details

Our top of the range high precision, vibrating microtome ('vibrotome' for short, but often referred to as a 'vibratome'), this is the finest tissue slicer in the world for preparations for visual patch clamping or high resolution imaging. The 7000smz series Vibrating microtome has been the instrument of choice for many labs for 10 years - over 450 labs and counting!

Using our microtomes, research detailing sectioning for visual patching of neurological tissue, heart, lung, and tissue scaffolds have all been published. The 7000smz-2 microtome represents significant advances with higher precision at a lower cost.

The vibrating mechanism of the 7000smz-2 microtome delivers unprecedented accuracy with nearly silent operation. Every machine is tested before dispatch by our in-house measurement devices and each machine is supplied with its own z-axis calibration checker.

The effect of excessive Z-axis deflection on the health and viability of the tissue preparation has been much discussed since the publication of Geiger et al (2003) and the Campden 7000smz-2 tissue slicer, with ≤ 1µm Z-axis deflection across a wide range of vibration speeds and amplitudes, delivers healthy viable sections every time.

The user interface is easy and versatile (with no foot switch unlike previous models) and offers simple operation at the push of a button or a range of changeable parameters for the expert user. The Campden 7000smz-2 also provides longevity of performance, as not only does the slicer give ≤ 1 µm performance out of the box, but the advance vibrating mechanism does not contain bearings and other elements subject to wear. Thus it will retain the ≤ 1 µm z-ad performance for years to come, giving you consistency in your biological preparation, without the need for expensive servicing.

Holding the tissue close to 4° C must continue throughout the slicing procedure. This can be done with passive cooling where a known amount of ice is used to maintain the cooled a.c.s.f. or with an electronically controlled thermo-electric Tissue Bath Cooler (7610A).

We have developed both ceramic and stainless steel microtome blades, alongside the machine, so that the grinding and honing facets for the blade edge are matched to the blade downward angle of orientation to the tissue. The ceramic blades have a particular advantage when slicing brain tissue older than 30 days. These ceramic microtome blades also have a second advantage in that unlike stainless blades, these do not have to be replaced after each tissue sample.

Other options include an LED cold light and magnifier or scope for clear observation whilst slicing. Shown with optional Slice incubation chamber and temperature controller.

Highlighted Accessory: Tissue Slice Recovery Chamber

Shown alongside the tissue slicer above, the Model 7470 Temperature-controlled Slice Holding Chamber was developed as an optional accessory to the Campden Instruments range of tissue slicers. They are designed to hold and maintain tissue slices in six sub-chambers at physiological temperatures with an aeration supply to allow recovery from slicing as well as incubation during the experimental day.

Specifications

Section thickness step size: 0.001 mm
Bath table rise & fall speed: 1.0 mm/sec maximum
Maximum (vertical) travel of bath table: 19 mm
Cutting head advance speed: Minimum: -4.0 mm/sec (-1.00 during slicing) Maximum: +4.0 mm/sec (+1.00 during slicing)
Cutting head retraction speed: 4.0 mm/sec
Maximum travel of cutting head: 40 mm
Blade oscillation frequency: Minimum: 50 Hz (lower frequenices available upon request) Maximum: 120 Hz (amplitude dependent)
Frequency step size: 5 Hz
Blade oscillation amplitude Minimum: 0.5 mm (nominal) Maximum: 2.5 mm (nominal)
Amplitude step size: 0.25 mm (nominal)
Power requirements (Selectable): 115VAC 60Hz, 230VAC 50Hz
Power rating: 100W
Fuse rating 115V: T2A 250VAC 230V: T2A 250VAC
Light source: 100-240Vac 3W
Dimensions: 410mm Width x 400mm Depth x 270mm Height (excluding light source and microscope)
Weight: 33Kg
Boxed shipping weight: 60Kg

Science

Preparation of viable adult ventricular myocardial slices from large and small mammals
Samuel A Watson, Martina Scigliano, Ifigeneia Bardi, Raimondo Ascione, Cesare M Terracciano & Filippo Perbellini

Nature Protocols volume 12, pages 2623-2639 (2017) - View Abstract

Free-of-Acrylamide SDS-based Tissue Clearing (FASTClear) for three dimensional visualization of myocardial tissue
Filippo Perbellini, Alan K. L. Liu, Samuel A. Watson, Ifigeneia Bardi, Stephen M. Rothery & Cesare M. Terracciano

Scientific Reports 7, Article number: 5188 (2017) - View Abstract

Accessories

Required Accessories

Ceramic Blades - 5 pack
Ceramic Blades - 5 pack
Model 7550-1-C

Specialized Ceramic blades for Campden Vibrating Microtomes. These blades are honed with a single bevel for superior slicing.

Stainless Steel Blades - 50 pack
Stainless Steel Blades - 50 pack
Model 7550-1-SS

Specialized Blade Technology for Campden Vibrating Microtomes.

Optional Accessories

Tissue Slice Recovery Chamber
Tissue Slice Recovery Chamber
Model 7470

This chamber has been designed to hold and maintain tissue slices in six sub-chambers at physiological temperatures with an aeration supply to allow recovery from slicing as well as incubation during the experimental day.

Bath Mount for Vibrating Microtomes
Bath Mount for Vibrating Microtomes
Model 7000-3-1A

Newly redesigned Bath Mount. Edge of the ice bath outer now has a rolled edge. Preventing vibration of the bath wall at certain harmonics of speed and amplitude, hence more stable, less splash, less evident vibration. Shown with standard and adjustable tissue mounts that can be ordered separately.

Temperature Controlled Standard Tissue Bath
Temperature Controlled Standard Tissue Bath
Model 7610A

Temperature controlled cooling baths for the 7000smz-2, 5000mz-2, 5100-Plus and 5100mz vibrotomes with a controllable temperature range of approx +10ºC to 0ºC with accuracy of ± 1 ºC. For experiments where exact control of a low slicing temperature is required.

Temperature Controlled Warming Tissue Bath
Temperature Controlled Warming Tissue Bath
Model 7611A

Physiological temperature controlled baths for the 7000smz-2, vibrotomes with a controllable temperature range of approx. +50 to +10ºC with accuracy of ± 1 ºC. For experiments utilising the technique of Huang S & Uusisaari MY (2013) where exact control of physiological slicing temperature is required.

Rectangular Tissue Mount
Rectangular Tissue Mount
Model 7000-4-3A

Rectangular specimen mount for dual specimen

Integrally Mounted Cold Light Source
Integrally Mounted Cold Light Source
Model CL200-1

To facilitate the careful slicing operation, it is most important that the progress of the blade through the tissue be clearly observed.

Integrally Mounted Magnifying Glass
Integrally Mounted Magnifying Glass
Model 7000-1-3

A magnifying glass for general global slices offering approximately 2x magnification.

Case for Campden 7000 Series Slicer
Case for Campden 7000 Series Slicer
Model 7000smz-Case

A deluxe transit case with wheels and handles for a lab that may need to relocate the machine.

Crate for 7000 Series Slicer
Crate for 7000 Series Slicer
Model 7000-60-1

Wooden crate in treated wood to IPPC standards for international shipment.

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