Trial-unique Nonmatching-to-Location Task - TUNL - for Rats
 

Trial-unique Nonmatching-to-Location Task - TUNL - for Rats

Model 89545-R

 

Details

TUNL can be thought of as a version of delayed nonmatching-to-place (DNMTP), in which the subjects are presented with a sample location and, following a delay, with the (incorrect, S-) sample location and a (correct, S+) nonmatching location. DNMTP has been shown to be vulnerable to non-spatial mediating strategies. TUNL eliminates these problems by using multiple, trial-unique locations, preventing the use of mediating strategies. Animals with lesions in the dorsal hippocampus or decreased hippocampal neurogenesis were impaired when the locations were close together, but not when they were far apart. This feature also renders the task exquisitely sensitive to hippocampal dysfunction, tapping both the role of the hippocampus in memory and in pattern separation.

Accessories

Required Accessories

Bussey-Saksida Rat Touch Screen Chamber Package
Bussey-Saksida Rat Touch Screen Chamber Package
Model 80604

Not just another square sheet metal box, the Bussey-Saksida chamber has a unique trapezoidal wall shape to focus the animal’s attention and is made from machined parts that simply slot together. The chamber can also be configured to a modular square chamber with panels, levers, lights, and a range of other operators.

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