Model npi.VA-10

  • Easy to use amplifier for voltammetric recordings
  • Detect the smallest signals with picoampere range sensitivity
  • FCV in the range of +/-1000 mV or +/-2000 mV
  • Easy DC amperometry with built-in voltage source
  • Connect carbon fiber electrodes
  • In vivo recording with optional mini-heastages (also multi-channel)
  • Also available as module for the EPMS-07 system


The VA-10X is a sensitive (picoampere range) current amplifier that is intended for voltammetric measurements. It can be used with carbon-fiber microelectrodes in biological systems, where the total currents do not exceed a few tens of nA, or with other electrode types. The current range can be customised with different feedback resistors, also a switchable headstage is available for higher flexibility during experiments.
Besides the current range, also filter frequencies, gain stages or headstages can be customised. If you require a special design, please let us know.
It was designed at the Max-Planck-Institute for Experimental Medicine in Göttingen as an economically priced alternative to do-it-yourself systems and expensive commercial systems.

It can be used for either DC amperometry using the built-in voltage source, or it can be operated with user-supplied external voltage waveforms (e.g. for cyclic voltammetry).
The VA-10X-8 is equipped with high performance 8-pole Bessel filters.

The device can be widely customised Ask npi electronic for headstages with different feedback resistors, multi electrode headstages, or miniaturised headstages for in-vivo recordings.

Optionally, the VA-10X can be equipped with a frequency booster in order to enhance the recording bandwidth to several kHz.

The device can be adapted to directly replace the discontinued Dagan Chem-Clamp.

The VA-10 is also available as module for the EPMS-07 system.


HEADSTAGE Input voltage range: ±1200 mV
Operating voltage: ±12 V
Enclosure: Size: 40 x 70 x 20 mm, driven shield (COMMAND potential)
Mounting plate: 50 x 70 mm, not conducting
Electrode connector:driven shield (COMMAND potential)
Ground connector: 1 mm connector (black)
Driven shield output: 1 mm connector (red)
Input resistance: >1013 Ω
Current range: ±20 nA
Feedback resistor: 500 MΩ (other values on request)
OUTPUTS Impedance: 250 Ω
FILTERED: BNC connector, sensitivity selectable with GAIN switch, FILTERED with LP Bessel FILTER
UNFILTERED: BNC connector, sensitivity selectable with GAIN switch
INPUTS Resistance: 1 MΩ
VOLTAGE SOURCE COMMAND VOLTAGE set by 10-turn potentiometer, range: (1000 mV, polarity selectable with polarity switch (+, 0, -), display XXXX mV
INPUT BNC connector, sensitivity: /10, also displayed
LP FILTER 8-pole Bessel FILTER
16 corner frequencies: 20, 50, 100, 200, 300 500, 700, 1k, 1.3k, 2k, 3k, 5k, 8k, 10k, 13k, 20k Hz. (other values on request)
GAIN 7-position rotary switch (x0.5, x1, x2.5, x5, x10, x25, x50 mV / pA) (other values on request)
POWER REQUIREMENTS 115/230 V AC, 60/50 Hz, fuse 0.4/0.2 A, slow.
DIMENSIONS 19″ rackmount cabinet, 19″ (483 mm), 10″ (250 mm), 3.5″ (88 mm)


Benoit, E., Schlumberger, S., Molgó, J., Sasaki, M., Fuwa, H., & Bournaud, R. (2022). Gambierol Blocks a K+ Current Fraction without Affecting Catecholamine Release in Rat Fetal Adrenomedullary Cultured Chromaffin Cells. Toxins, 14(4). https://doi.org/10.3390/toxins14040254

Rahman, A. A., Masango, P., Stavely, R., Bertrand, P., Page, A., & Nurgali, K. (2023). Oxaliplatin-Induced Damage to the Gastric Innervation: Role in Nausea and Vomiting. Biomolecules, 13(2). https://doi.org/10.3390/biom13020276

Gvozdik, N. A., Kurbatova, A. A., Ovsyannikov, N. A., Pogosova, M. A., & Stevenson, K. J. (2022). Influence of conductive additives in a nano-impact electrochemistry study of single LiMn2O4 particles. Electrochemistry Communications, 139. https://doi.org/10.1016/j.elecom.2022.107304

Al Saedi, A., Sharma, S., Bani Hassan, E., Chen, L., Ghasem-Zadeh, A., Hassanzadeganroudsari, M., Gooi, J. H., Stavely, R., Eri, R., Miao, D., Nurgali, K., & Duque, G. (2022). Characterization of Skeletal Phenotype and Associated Mechanisms With Chronic Intestinal Inflammation in the Winnie Mouse Model of Spontaneous Chronic Colitis. Inflammatory Bowel Diseases, 28(2), 259–272. https://doi.org/10.1093/ibd/izab174


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