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Slice and In-Vitro Electrophysiology > Vibrating Microtomes > Campden Vibrating Microtomes

VIBRATING MICROTOME 7000

Model 7000smz-2

Vibrating Microtome 7000
 
   
 

DETAILS

Our top of the range high precision, vibrating microtome, this is the finest tissue slicer in the world for preparations for visual patch clamping or high resolution imaging.

Using the predecessor, the Integraslice, sectioning for visual patching of neurological tissue, heart and lung have all been published. The new 7000smz-2 microtome represents a significant advance with higher precision AND at a lower cost.

The all-new vibrating mechanism of the 7000smz-2 microtome, developed after 2 years of extensive R&D by our engineers delivers unprecedented accuracy with nearly silent operation. Every machine is tested before dispatch by our in-house measurement devices and each machine is supplied with its own z-axis calibration checker.

The effect of excessive Z-axis deflection on the health and viability of the tissue preparation has been much discussed since the publication of Geiger et al (2003) and the Campden 7000smz-2 tissue slicer, with ≤ 1µm Z-axis deflection across a wide range of vibration speeds and amplitudes, delivers healthy viable sections every time.

The all-new user interface is easy and versatile (with no foot switch unlike previous models) and offers simple operation at the push of a button or a range of changeable parameters for the expert user. The Campden 7000smz-2 also provides longevity of performance, as not only does the slicer give ≤ 1 µm performance out of the box, but the advance vibrating mechanism does not contain bearings and other elements subject to wear. Thus it will retain the ≤ 1 µm z-ad performance for years to come, giving you consistency in your biological preparation, without the need for expensive servicing.

Holding the tissue close to 4° C must continue throughout the slicing procedure. This can be done with passive cooling where a known amount of ice is used to maintain the cooled a.c.s.f. or with an electronically controlled thermo-electric Tissue Bath Cooler (7610A).

We have developed both ceramic and stainless steel microtome blades, alongside the machine, so that the grinding and honing facets for the blade edge are matched to the blade downward angle of orientation to the tissue. The ceramic blades have a particular advantage when slicing brain tissue older than 30 days. These ceramic microtome blades also have a second advantage in that unlike stainless blades, these do not have to be replaced after each tissue sample.

Other options include an LED cold light and magnifier or scope for clear observation whilst slicing.

FEATURES

SPECIFICATIONS

DOWNLOADS

PRODUCT MANUALS

Models 7000smz and 5000mz Vibrating Blade Tissue Slicers Instruction Manual

RESEARCH PAPERS AND BIBLIOGRAPHIES

Integraslice Bibliography
Isolated Living Heart Slices from Adult Rats and Guinea Pgs as a Model for Drug Testing
MEA recordings from acute heart slices from adult rats and guinea pigs
Rhythmicity without Synchrony in the Electrically Uncoupled Inferior Olive
NPL consultancy on oscillating movement featured it in their “Engineering Precisely” Newsletter
Field and Action Potential Recordings in Heart Slices: Correlation with established In Vitro and In Vivo Models
Cardiac tissue slices with prolonged survival for in vitro drug safety screening
Innovation in safety pharmacology testing
Methodological innovations expand the safety pharmacology horizon

ACCESSORIES

REQUIRED ACCESSORIES

Ceramic Blades - 5 pack Image

Ceramic Blades - 5 pack
Model 7550-1-C

Specialized Ceramic blades for Campden Vibrating Microtomes. These blades are honed with a single bevel for superior slicing.

Stainless Steel Blades - 50 pack Image

Stainless Steel Blades - 50 pack
Model 7550-1-SS

Specialist Blade Technology for Campden Vibrating Microtomes.

OPTIONAL ACCESSORIES

Bath Mount for Vibrating Microtomes Image

Bath Mount for Vibrating Microtomes
Model 7000-3-1A

Newly redesigned Bath Mount. Edge of the ice bath outer now has a rolled edge. Preventing vibration of the bath wall at certain harmonics of speed and amplitude, hence more stable, less splash, less evident vibration.

Temperature Controlled Warming Tissue Bath Image

Temperature Controlled Warming Tissue Bath
Model 7611A

Physiological temperature controlled baths for the 7000smz-2, vibrotomes with a controllable temperature range of approx. +50 to +10ºC with accuracy of ± 1 ºC. For experiments utilising the technique of Huang S & Uusisaari MY (2013) where exact control of physiological slicing temperature is required.

Integrally Mounted Cold Light Source Image

Integrally Mounted Cold Light Source
Model CL200

To facilitate the careful slicing operation, it is most important that the progress of the blade through the tissue be clearly observed.

Integrally Mounted Magnifying Glass Image

Integrally Mounted Magnifying Glass
Model 7000-1-3

A magnifying glass for general global slices offering approximately 2x magnification.

RELATED PRODUCTS

Dual channel PTFE chamber system for Electrophysiology with heater & thermistor feedback control Image

Dual channel PTFE chamber system for Electrophysiology with heater & thermistor feedback control
Model CI.7450-2P(E)

The new all-in-one chamber design incorporates the best features of both the old Haas or interface type cell and the old Oslo or submerged type cell.

Dual channel Acrylic chamber system for Electrophysiology with heater & thermistor feedback control Image

Dual channel Acrylic chamber system for Electrophysiology with heater & thermistor feedback control
Model CI.7450-2A(E)

The new all-in-one chamber design incorporates the best features of both the old Haas or interface type cell and the old Oslo or submerged type cell.

Visual Patching and Imaging Chamber Image

Visual Patching and Imaging Chamber
Model 7800

Consists of an aluminium heat exchanger plate heated by a thin heating element. The heat exchanger supplies concentric heat to the chamber itself and in-line heat to the incoming perfusate ensuring both are heated uniformly.

Quad channel Acrylic chamber system for Electrophysiology with heater & thermistor feedback control Image

Quad channel Acrylic chamber system for Electrophysiology with heater & thermistor feedback control
Model CI.7450-4A(E)

The new all-in-one chamber design incorporates the best features of both the old Haas or interface type cell and the old Oslo or submerged type cell.

Hex channel PTFE chamber system for Biochemistry with heater & thermistor feedback control Image

Hex channel PTFE chamber system for Biochemistry with heater & thermistor feedback control
Model CI.7450-6P(B)

The new all-in-one chamber design incorporates the best features of both the old Haas or interface type cell and the old Oslo or submerged type cell.

Hex channel Acrylic chamber system for Biochemistry with heater & thermistor feedback control Image

Hex channel Acrylic chamber system for Biochemistry with heater & thermistor feedback control
Model CI.7450-6A(B)

The new all-in-one chamber design incorporates the best features of both the old Haas or interface type cell and the old Oslo or submerged type cell.

Quad channel PTFE chamber system for Electrophysiolgy with heater & thermistor feedback control Image

Quad channel PTFE chamber system for Electrophysiolgy with heater & thermistor feedback control
Model CI.7450-4P(E)

The new all-in-one chamber design incorporates the best features of both the old Haas or interface type cell and the old Oslo or submerged type cell.

CONTACT US

Campden Instruments LTD
P.O. Box 8148
Loughborough, Leics.,
LE12 7XT. England

Tel: +44 1509 814790

uksales@campdeninstruments.com

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CONTACT US

Campden Instruments LTD
P.O. Box 8148
Loughborough, Leics.,
LE12 7XT. England

Tel: +44 1509 814790

uksales@campdeninstruments.com

Copyright © 2009 - 2017 Campden Instruments LTD. All Rights Reserved.