RAT CNOR-OL EXPERIMENT AND HOLDING CHAMBER

DETAILS

Rat cNOR-OL Experiment and Holding Chamber allows choice of Floor type and Gate type. Additional options of scoring camera and food reward dispenser are also available.

A budget-friendly manual chamber provides an entry level for both cNOR/OL. No PC required, just plug the USB scoring chamber into your laptop and the scoring app will be triggered by the opening of the gate.

SCIENCE

Key Publications

• Ennaceur & Delacour 1988 (Object preference)
• Ennaceur & Meliani 1992 (Memory for location)
• Ennaceur & Aggleton 1997 (Prh lesions in spatial and NOR)
• Dix & Aggleton 1999 (Object-location)
• Dix & Aggleton 1999 (Object-context)
• Easton, Eacott, Zinkivskay 2005; Eacott & Norman 2004 (Combinations, Episodic memory)
• Eacott & Gaffan 2005; Easton & Eacott 2010 (Variety of different memories, dissociation of underlying mechanisms)
• Varghese, Brett, Harland, Van-Nobelen & John Dalrymple-Alford, 2009 Episodic memory, odour context
• Davies, Easton, Eacott, Gigg 2013 Episodic memory for WWW & Episodic memory & Alzheimer's-like pathology

Continual Trials NOR & OL

• Ameen-Ali, Easton & Eacott 2012 (rats)
• Ameen-Ali et al 2015 (improved reliability & interpretation)
• Seel, Eacott, Langston & Easton 2017 (rats)

Continual Trials 2018-2019 Papers

• Chan, M, Austen, J. M., Eacott, M. J., Easton, A. & Sanderson, D. J. (2019). The NMDA receptor antagonist MK-801 fails to impair long-term recognition memory in mice when the state-dependency of memory is controlled. Neurobiology of Learning and Memory 161: 57-62. - Abstract
• Cholinergic input to the hippocampus is not required for a model of episodic memory in the rat, even with multiple consecutive events. Behavioural Brain Research, Volume 354, Pages 48-54 15 November 2018, S. V. Seel, M. J. Eacott, R. F. Langston, A. Easton Behavioural Brain Research 354: 48-54. - Abstract
• Continual Trials Spontaneous Recognition Tasks in Mice: Reducing Animal Numbers and Improving Our Understanding of the Mechanisms Underlying Memory. Frontiers In Behavioural Neuroscience 13 September 2018, Chan, Eacott, Sanderson, Wang, Sun & Easton Frontiers in Behavioral Neuroscience 12: 214. - Abstract

Related papers on Recognition and Episodic Memory

• Pereda, D., Al-Osta, I., Okorocha, A.E., Easton, A. & Hartell, N.A. (2019). Changes in presynaptic calcium signalling accompany age-related deficits in hippocampal LTP and cognitive impairment. Aging Cell 18(5): e13008. - Abstract
• Incidental context information increases recollection. Learning & Memory 24(3): 136-139. - Abstract
• Ameen-Ali, K.E., Easton, A. & Eacott, M.J. (2015). Moving beyond standard procedures to assess spontaneous recognition memory. Neuroscience and Biobehavioral Reviews 53: 37-51. - Abstract
• Robertson, B-A., Eacott, M.J. & Easton, A. (2015). Putting Memory in Context: Dissociating memories by distinguishing the nature of context. Behavioural Brain Research 285: 99-104. - Abstract
• Davis, KE, Easton, A., Eacott, MJ & Gigg, J (2013). Episodic-Like Memory for What-Where-Which Occasion is Selectively Impaired in the 3xTgAD Mouse Model of Alzheimer's Disease. Journal of Alzheimer's Disease 33(3): 681-698. - Abstract
• Davis, K.E., Eacott, M.J., Easton, A & Gigg, J. (2013). Episodic-like memory is sensitive to both Alzheimer's-like pathological accumulation and normal ageing processes in mice. Behavioural Brain Research 254: 73-82. - Abstract
• Ameen-Ali,K.E., Eacott,M.J. & Easton,A. (2012). A new behavioural apparatus to reduce animal numbers in multiple types of spontaneous object recognition paradigms in rats. Journal of neuroscience methods 211(1): 66-76. - Abstract
• Easton, A & Eacott, MJ (2012). Cholinergic mechanisms of episodic memory: what specific behavioural tasks can tell us about specific neural mechanisms. Brain Research Bulletin. - Abstract
• Easton, A, Webster, LAD & Eacott, MJ (2012). The episodic nature of episodic-like memories. Learning & Memory 19(4): 146-150. - Abstract
• Easton, A., Child, S. & Lopez-Crespo, G. (2011). Differential outcomes aid the formation of categorical relationships between stimuli. Behavioural Brain Research 222(1): 270-273. - Abstract
• Easton, A., Fitchett, A., Eacott, M.J. & Baxter, M.G. (2011). Medial septal cholinergic neurons are necessary for context-place memory but not episodic-like memory. Hippocampus 21(9): 1021-1027. - Abstract
• Eacott, MJ & Easton, A (2010). Episodic memory in animals: Remembering which occasion. Neuropsychologia 48(8): 2273-2280. - Abstract

ACCESSORIES

OPTIONAL ACCESSORIES

Rat cNOR-OL Manual Gate
Model CI.80514R-4

Rat cNOR-OL manual gate with microswitch for camera trigger.

Rat cNOR-OL Auto-gate
Model CI.80514R-5

Rat cNOR-OL Auto-gate with 'E' and 'H' chamber photobeams, recording direction of travel and camera trigger.

Rat cNOR-OL Experiment Chamber Fixed Floor
Model CI.80514R-2

Liquid Feeder, Reward Trough and Mounting bracket for Rat cNOR-OL Chamber
Model CI.80514R-P45

Rat cNOR-OL Experiment Chamber Sliding Floor
Model CI.80514R-3

Rat cNOR-OL Experiment chamber sliding floor with magnetic mounting for changing context floors.

Rat cNOR-OL Experiment Chamber Context Change Floors
Model CI.80514R-3-5

Five context change floors of different textures for Rat cNOR-OL Experiment chamber. Enables the chamber to be used for the "What-Where-Which" Task for Episodic Memory.

Rat cNOR-OL Camera Mount
Model CI.80514R-6

Rat cNOR-OL camera mount sub-assembly with speaker for white noise.